﻿<?xml version="1.0" encoding="utf-8"?><rss xmlns:a10="http://www.w3.org/2005/Atom" version="2.0"><channel><title>מאמרים אחרונים מאת צך</title><link>/Authors/Author6671.aspx?rss=1</link><description>מאמרים אחרונים מאת צך אקדמיקס - ספריית המאמרים של ישראל</description><item><link>/Articles/Article53825.aspx</link><title>ד&quot;ר אלה פישמן - Targeted elimination of cells expressing the high affinity receptor for IgE (FcRI) by a Pseudomonas exotoxin-based chimeric protein</title><description>מבוסס על מאמרן של ד&quot;ר אלה פישמן ו Haya Lorberboum-Galski


The immunogenicity of the toxin moiety
of the chimeric protein can also be reduced by adapting various techniques like mutagenesis. Keeping these points in mind, the clinical application of this chimeric protein becomes an effective anti-allergy treatment. The cyto-toxicity of such fusion proteins can lead to an attractive treatment option of diseases like cancer etc.</description><pubDate>Sun, 22,Apr 2012 01:02:23</pubDate></item><item><link>/Articles/Article53824.aspx</link><title>ד&quot;ר אלה פישמן - TARGETED Fc2’-3-PE40 CHIMERIC PROTEIN ABOLISHES PASSIVE CUTANEOUS ANAPHYLAXIS IN MICE</title><description>מבוסס על מאמרים של ד&quot;ר אלה פישמן, , D. PRUS*, R. BELOSTOTSKY &amp; H. LORBERBOUM-GALSKI 

This chimeric protein can be developed as new generation treatment as it shows clinical superiority over other major groups of drugs like 2-agonists, methylxantines, glucocorticoids, antihistamines and chromolyn sodium etc. which are unable to prevent the allergic reaction and can only reverse or block its effects and also have side-effects. The use of similar chimeric molecules will offer a new hope for treat</description><pubDate>Sun, 22,Apr 2012 01:01:17</pubDate></item><item><link>/Articles/Article53823.aspx</link><title>ד&quot;ר אלה פישמן - Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability</title><description>מבוסס על מאמרם של ד&quot;ר אלה פישמן, Andrei V Budanov, Tzipora Shoshani, Alexander Faerman, Elena Zelin, Iris Kamer, Hagar Kalinski, Svetlana Gorodin, Ayelet Chajut, Paz Einat, Rami Skaliter, Andrei V Gudkov, Peter M Chumakov and Elena Feinstein

Therefore Hi95 is linked to the regulation of cell growth and survival. The characterization of Hi95 helps researchers in finding out novel therapeutics against stroke and heart attack. Thus the identification of various cell signaling pathways that are re</description><pubDate>Sun, 22,Apr 2012 12:59:29</pubDate></item><item><link>/Articles/Article53822.aspx</link><title>ד&quot;ר יואב מיניסטר - Allicin and disulfiram enhance platelet integrin αIIbβ3-fibrinogen binding</title><description>מבוסס על מאמרם של ד&quot;ר יואב מיניסטר, בוריס שנקמן, נורית רוזנברג ונפתלי סביון

These effects could be obtained by a plasma concentration of Allicin that can be achieved by consuming 4-5 garlic cloves per day, thus suggesting an effective measure to prevent thrombosis. Also it proves the efficacy of similar organosulfur compounds in cancer.</description><pubDate>Sun, 22,Apr 2012 12:53:49</pubDate></item><item><link>/Articles/Article53819.aspx</link><title>ד&quot;ר מקסים סקסונוב - Clcn5 Knockout Mice Exhibit Novel Immunomodulatory Effects and Are More Susceptible to Dextran Sulfate Sodium-Induced Colitis</title><description>מבוסס על מאמרם של ד&quot;ר מקסים סקסונוב, Philip Alex, Mei Ye, Nicholas C. Zachos, Jennifer Sipes, Thuan Nguyen, , Liberty Gonzales, Zubin Arora, Ting Zhang, Michael Centola, Sandra E. Guggino, and Xuhang Li

This research can thus provide new effective individually tailored strategies to generate novel and efficient therapeutic targets for the management of diarrhea and other symptoms in ulcerative colitis patients. Since many ion transporter proteins have been linked with cancer, it would be intere</description><pubDate>Sun, 22,Apr 2012 11:25:45</pubDate></item><item><link>/Articles/Article53362.aspx</link><title>The Mosaic of Autoimmunity: Genetic Factors Involved in Autoimmune Diseases - ד&quot;ר אוריאל כץ, Yehuda Shoenfeld, Boris Gilburd, Mahmud Abu-Shakra, Howar</title><description>מבוסס על מאמרם של ד&quot;ר אוריאל כץ - Yehuda Shoenfeld, Boris Gilburd, Mahmud Abu-Shakra, Howard Amital, Ori Barzilai, Yackov Berkun, Miri Blank, Gisele Zandman-Goddard, Uriel Katz, Ilan Krause, Pnina Langevitz, Yair Levy, Hedi Orbach, Vitor Pordeus, Maya Ram, Yaniv Sherer, Elias Toubi and Yaron Tomer 
Since IgA levels have been associated with the progression of different cancers also, the development of such ‘mosaic’ for cancer might give a new direction to the therapeutics.</description><pubDate>Sun, 15,Apr 2012 02:30:03</pubDate></item><item><link>/Articles/Article53360.aspx</link><title>The Mosaic of Autoimmunity: Prediction, Autoantibodies, and Therapy in Autoimmune Diseases - ד&quot;ר אוריאל כץ, Yehuda Shoenfeld, Miri Blank, Mahmoud Abu-</title><description>מבוסס על מאמרם של ד&quot;ר אוריאל כץ Yehuda Shoenfeld, Miri Blank, Mahmoud Abu-Shakra, Howard Amital, Ori Barzilai, Yackov Berkun, Nicola Bizzaro, Boris Gilburd, Gisele Zandman-Goddard, Uriel Katz, Ilan Krause, Pnina Langevitz, Ian R. Mackay, Hedi Orbach, Maya Ram, Yaniv Sherer, Elias Toubi and M. Eric Gershwin

The modulation of cells of immune system like T cells etc. also has been proved to be benificial against autoimmune diseases. Thus these different factors can be used forsuccessful prediction</description><pubDate>Sun, 15,Apr 2012 02:27:25</pubDate></item><item><link>/Articles/Article53359.aspx</link><title>Evidence for the Use of Intravenous Immunoglobulins—A Review of the Literature - ד&quot;ר אוריאל כץ, Shaye Kivity, Uriel Katz, Natalie Daniel, Udi Nussinov</title><description>מבוסס על מאמרם של ד&quot;ר אוריאל כץ - Shaye Kivity, Uriel Katz, Natalie Daniel, Udi Nussinovitch, Neophytos Papageorgiou, Yehuda Shoenfeld

 IVIg treatment was suggested to be effective for systemic and kidney diseases, Systemic sclerosis, severe chronic Juvenile rheumatoid arthritis, myopathies, Acquired hypogammaglobulinemia too and can reduce HIV infections in children. Since cancer is characterized by high inflammation, the use of immunoglobulins for the treatment of cancer might be an interesti</description><pubDate>Sun, 15,Apr 2012 02:22:59</pubDate></item><item><link>/Articles/Article53358.aspx</link><title>Autoantibody Explosion In Antiphospholipid Syndrome - ד&quot;ר אוריאל כץ, יהודה שונפלד, גלעד טויג, יניב שרר</title><description>מבוסס על מאמרים של ד&quot;ר אוריאל כץ, יהודה שונפלד, גלעד טויג, יניב שרר
The routine testing for the presence of other antiphospholipid antibodies is expensive and does not improve the diagnosis of APS significantly, even when these antiphospholipid antibodies like antiphosphatidylserine, antiphosphatidylethanolamine, antiphosphatidylglycerol, antiphosphatidic acid and antiphosphatidylinositol etc. are more specific for APS. A similar approach can be used in cancer where phospholipid metabolites can</description><pubDate>Sun, 15,Apr 2012 02:19:55</pubDate></item></channel></rss>